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23.-25.11.2022 TRR225/GRK2157 Symposium “Biofabrication meets Infection”

By 8. November 2022November 30th, 2022Events

PhD students of the SFB/TRR 225 Collaborative Research Centre “Biofabrication” and the GRK2157 “3D Infect” research group were organizing an amazing joint international symposium “Biofabrication meets Infection”, which took place on the 23 – 25. November 2022 at the Rudolf Virchow Center in Wuerzburg (Germany).

Numerous high-profile speakers participated in this event.

This international symposium was focusing primarily on topics of biofabrication and complex tissue models.

Welcome to the Biofabrication meets Infection Symposium 2022,

On behalf of the scientific and local organization committees, we would like to welcome you to our joint international symposium “Biofabrication meets Infection”.

Biofabrication concerns the fabrication of stratified three dimensionally organized cell-material constructs, with the aim to generate biologically functional tissue models. The SFB/TRR 225 consortium is focused on this field of research. The GRK2157 on the other hand deals with the application of 3D tissue models for infection research. Both consortia have joined forces to organize this international symposium which will focus on topics related to biofabrication and complex tissue models and their application to infection research based on this unique local clustering of expertise in these fields.

The objective of this conference is to provide a broad communication platform for this multi-disciplinary community to enable exchange between researchers working in the fields of biofabrication, tissue model development and infection research to identify synergies and boost new research ideas and cooperations.


We want to highlight that the symposium has been organized by PhD students from the SFB/TRR 225 and the GRK2157 in a joined effort and want to thank the students for the fantastic job they have done. We furthermore thank the speakers for their commitment and contributions and are confident that the scientific program composed of 25 lectures and XX posters will stimulate excellent scientific discussions.

Würzburg is a historic city with a rich culture and the renowned residence palace, a UNESCO world cultural heritage and one of the most important baroque palaces in Europe. And it is also a lively University city with a famous local wine culture and lovely country sides.

We are looking forward to a conference with exciting science, stimulating discussions and exchange and multiple opportunities to initiate collaborations!

Jürgen Groll and Thomas Rudel


Scientific Board

  • Sina Bartfeld, Institute for Molecular Infection Biology, University of Würzburg / Medical Biotechnology, Technical University Berlin
  • Jürgen Groll, Department for Functional Materials in Medicine and Dentistry, University of Würzburg
  • Tomasz Jüngst, Department for Functional Materials in Medicine and Dentistry, University of Würzburg
  • Vera Kozjak-Pavlovic, Department of Microbiology, University of Würzburg
  • Marco Metzger, Fraunhofer Translational Center Regenerative Therapies TLC-RT, Würzburg, Germany
  • Jennifer Ritzer, Department for Functional Materials in Medicine and Dentistry, University of Würzburg
  • Thomas Rudel, Department of Microbiology, University of Würzburg
  • Jörg Teßmar, Department for Functional Materials in Medicine and Dentistry, University of Würzburg

Local Organizing Committee

This symposium is kindly sponsored by:

Biomol GmbH Hamburg

I&L Biosystems

GeSiM GmbH


Wednesday, November 23, 2022 (internal meeting of TRR225 and GRK2157 members)

2:00 pm

Arrival of TRR225 and GRK2157 members and attachment of posters

3:00 – 4:00 pm Jürgen Groll and Thomas RudelWelcome and Introduction (RVZ lecture Hall)
4:00 – 5:30 pm

Internal poster session

PhD students of TRR225 and GRK2157

5:30 – 6:00 pm

Internal meeting with SFB TRR225 and GRK2157 members

PhD students of TRR225 and GRK2157

6:00 – 8:30 pm

Welcome reception / Get together

Wednesday, November 24, 2022

8:00 am Arrival of external participants and attachment of posters
9:00 – 9:30 am
Jürgen Groll and Thomas RudelWelcome and Introduction (RVZ lecture Hall) Session I: Biofabricated tissue models
9:30 – 10:00 am

Jos Malda, University Medical Center Utrecht, Netherlands

Converged Biofabrication technologies for 3D implants and models

10:00 – 10:30 am

Daniela Duarte Campos, University Heidelberg, Germany

Bioprinting for tissue and organ engineering (digital) 

10:30 –11:00 am

Heunsgoo Shin, Hanyang University Seoul, South Korea

Engineering multi-cellular spheroids using bioinspired materials for biofabrication of 3D tissue

11:00 – 11:30 am Coffee Break / Poster Session Session II: Cellular guidance structures
11:30 – 12:00 am

Jochen Salber, Ruhr Universität Bochum, Germany

From single-cell control to coordinated vascular-nerve bundle extrusion to complex tissues and organs – The cooperativity of molecular gradients and guidance structures

12:00 – 12:30 pm

Laura DeLaporte, RTWH Aachen, Germany

Injectable synthetic colloidal building blocks to assemble into structured 3D tissue engineering constructs

12:30 – 12:45 pm

Marie Piantino, Osaka University, Japan

Development of a three-dimensional blood-brain barrier network with opening capillary structures for drug transport screening assays (selected talk #3)

12:45 – 1:45 pm Lunch Break / Poster Session Session III: Vascularization

1:45 – 2:15 pm

Debby Gawlitta, University Medical Center Utrecht, Netherlands

Designing the vascular tree in complex tissue models

2:15 – 2:45 pm

Michiya Matsusaki, Osaka University, Japan

Vascularized 3D Tissue Models for Infection Assays of Cancer Cells and Bacteria

2:45 – 3:00 pm

3:00 – 3:30 pm

Matthias Ryma, University Würzburg, Germany

Sacrificial templating via thermoresponsive polymers for simple, reproducible, and accurate in vitro vascularization (selected talk #4, 49, 53)
Coffee Break / Poster Session Session IV: Organoids and 3D Infection models

3:30 – 4:00 pm

Andrew Thorely, Genentech, USA

Use of primary human lung cells to model epithelial-macrophage innate immune responses (digital)

4:00 – 4:30 pm

Daniel J. Kelly, Trinity College Dublin, Ireland

Biofabrication and bioprinting for bone and joint regeneration

4:30 – 5:00 pm

5:00 – 5:30 pm

6:00 – 7:00 pm

7:30 – 10:00 pm

Matthias Lutolf, EPFL Lausanne, Switzerland

Engineering organoids (digital)

Francesco Boccellato, University of Oxford, UK

Stem-cell driven models to understand epithelial response to infections and cancer initiation
Guided tour with Night-watchmenMeeting point: Vierröhrenbrunnen, Beim Grafeneckart 12, Würzburg
Symposium DinnerRestaurant Bürgerspital Weinstuben, Theater Strasse 19, Würzburg

Friday, November 25, 2022

9:00 – 9:30 am Session I: Biofunctionalization and cell tracking Ana Paula Pego, University of Porto, PortugalEngineering the nervous system with the help of biomaterials
9:30 – 10:00 am

Viola Vogel, ETH Zürich, Switzerland

Mechanobiology of platelets

10:00 – 10:30 am

10:30 – 10:45 am

10:45 – 11:00 am

11:00 – 11:15 am

11:15 – 11:30 am

 Ali Doryab, Helmholtz-Zentrum München, Germany

A Bioinspired “Breathing” In Vitro Mini-Lung Fibrosis Model

Niklas Pallmann, University Würzburg, Germany

Airway tissue models based on a novel synthetic scaffold to replace animal experiments (selected talk #24, 30)

Ivana Jeremic, University Erlangen-Nürnberg, Germany

Quantitative imaging and analysis of biofabricate quality and maturation (selected talk #35)

David Böhringer, University Erlangen-Nürnberg, Germany

Traction forces of migrating immune cells” (selected talk #5, 47)Coffee BreakSession II: Advanced human infection models

11:30 – 12:00 am            

Eileen Gentleman, Kings College London, UK

Modular hydrogels for organoid-based disease modelling (digital)

12:00 – 12:15 pm            

Leo Endres, University Würzburg, Germany

Modeling Neisseria meningitidis interaction with the meningeal blood-CSF barrier using iPSC and multi-cell culture approaches (selected talk #16)

12:15 – 12:30 pm 


Thomas Däullary, University Würzburg, Germany

Salmonella Typhimurium infection in a primary in vitro model of the human small intestine reveals the induction of OLFM4 expression as host cell response” (selected talk #21, 32, 55)

12:30 – 1:00 pm Lunch Break Session III: Virulence factors in infection
1:15 – 1:45 pm            

Mikael Sellin, Uppsala University, Sweden

Pathogen Attack on the Intestinal Epithelium – Insights from Enteroid Imaging 

1:45 – 2:15 pm            

Steve Boulant, University of Florida, USA

Understanding enteric virus-host interactions at the single cell level using intestinal organoids (digital)

2:15 – 2:30 pm           

2:30 – 3:00 pm

Mindaugas Pauzuolis, University Würzburg, Germany

Helicobacter pylori shows tropism to gastric differentiated pit cells dependent on urea chemotaxis (selected talk #6)
Awards and closing remarks Snacks and Departure