A08 | Vascular supply for 3D tissue based on shape-changing polymers and recombinant spider silk
The aim of this project is the fabrication of hierarchically structured tissues with integrated fiber-based structures, which give the matrix anisotropic properties for directed cell growth, as well as tubular elements for the supply of nutrients and oxygen. To implement the project, various manufacturing methods such as 4D biofabrication approaches and established 3D printing and fiber spinning processes will be combined. The integrated tubular structures should also provide a basis for a later vascularization of the constructs after tissue maturation.