Publications 2024

Antonelli Y, Krüger R, Buehler A, Monavari M, Fuentes-Chandía M, Colombo F, Palmisano R, Boßerhoff AK, Kappelmann-Fenzl M, Schödel J, Boccaccini AR, Selhuber-Unkel C, Letort G, Leal-Egaña A. When Mechanical Stress Matters. Generation of Polyploid Giant Cancer Cells in Tumor-Like Microcapsules. Adv. Funct. Material doi:10.1002/adfm.202311139 (2024).  (C03, Z03)

Ascheid D, Baumann M, Pinnecker J, Friedrich M, Szi-Marton D, Medved C, Bundalo M, Ortmann V, Öztürk A, Nandigama R, Hemmen K, Ergün S, Zernecke A, Hirth M, Heinze KG, Henke E. A vascularized breast cancer spheroid platform for the ranked evaluation of tumor microenvironment-targeted drugs by light sheet fluorescence microscopy. Nature Communications, doi: 10.1038/s41467-024-48010-z. (2024). (Z02)

Bettendorf E, Schmid R, Horch RE, Kengelbach-Weigand A, Kulike Y, Schrüfer S, Schubert DW, Lamberger Z, Stahlhut P, Lang G, Sörgel CA. Bioprinted keratinocyte and stem cell laden constructs for skin tissue engineering. IJB doi: 10.36922/ijb.3925 (2024). (C03, A07, C04)

Bider F, Miola M, Clejanu C-E, Götzelmann J, Kuth S, Vernè E, Basu B, Boccaccini AR. 3D bioprinting of multifunctional alginate dialdehyde (ADA)–gelatin (GEL) (ADA-GEL) hydrogels incorporating ferulic acid. International Journal of Biological Macromolecule, doi: 10.1016/j.ijbiomac.2023.128449 (2024). (A01)

Cianciosi A, Pfeiffle M, Wohlfahrt P, Nürnberger S, Jungst T. Optical Fiber-Assisted Printing: A Platform Technology for Straightforward Photopolymer Resins Patterning and Freeform 3D Printing. bioRxiv, doi: 10.1101/2024.01.17.576081 (2024). (B09, C02)

Ege D, Lu H, Boccaccini AR. Bioactive Glass and Silica Particles for Skeletal and Cardiac Muscle Tissue Regeneration. TISSUE ENGINEERING doi: 10.1089/ten.teb.2023.0277 (2024). (B03)

Doryab A, Braig J, Jungst T, Ryma M, Groll J. Fabrication Strategies for Bioinspired and Functional Lung-on-Chips. Adv. Funct. Mater. doi: 10.1002/adfm.20240772 (2024). (B02, B04, B09)

Gensler M, Malkmus C, Ockermann P, Möllmann M, Hahn L, Salehi S, Luxenhofer R, Boccaccini AR, Hansmann J. Perfusable Tissue Bioprinted into a 3D-Printed Tailored Bioreactor System. Bioengineering, doi: 10.3390/bioengineering11010068 (2024). (A03, B03)

Gupta R, Dittmeier M, Wohlleben G, Nickl V, Bischler T, Luzak V, Wegat V, Doll D, Sodmann A, Bady E, Langlhofer G, Wachter B, Havlicek S, Gupta J, Horn E, Luningschror P, Villmann C, Polat B, Wischhusen J, Monoranu CM, Kuper J, Blum R. Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene. Cancer Gene Therapy, doi: 10.1038/s41417-024-00809-0 (2024).  (C05)

Gutmann M, Reinhardt D, Seidensticker C, Raschig M, Hahn L, Moscaroli A, Behe M, Meinel L, Lühmann T. Matrix Metalloproteinase-Responsive Delivery of PEGylated Fibroblast Growth Factor 2. ACS Biomater. Sci. Eng., doi: 10.1021/acsbiomaterials.3c01511 (2023). (B06)

Heck AG, Nuhn L. Restoring the pH-responsiveness for amine-conjugated 2-propionic-3-methylmaleic anhydride linkers. Org. Chem. Front., doi: 10.1039/D4QO01077A (2024). (B05)

Horder H, Böhringer D, Endrizzi N, Hildebrand LS, Cianciosi A, Stecher S, DusiF, Schweinitzer S, Watzling M, Groll J,  Jüngst T, Teßmar L, Bauer-Kreisel P, Fabry B, Torsten B. Cancer cell migration depends on adjacent ASC and adipose spheroids in a 3D bioprinted breast cancer model. Biofabrication doi: 10.1088/1758-5090/ad57f7 (2024). (C02, A01, A02, B09)

Jablonka S, Schäfer N. The SMA Modifier Plastin 3 Targets Cell Membrane-Associated Proteins in Motoneurons. Neuroscience Insights, doi: 10.1177/26331055241226623 (2024). (A07)

Kah D, Lell J, Wach T, Spörrer M, Dessalles CA, Wiedenmann S, Gerum RC, Vergarajauregui SL, Esser TU, Böhringer D, Engel FB, Thievessen I, Fabry B. Contractility of cardiac and skeletal muscle tissue increases with environmental stiffness. bioRxiv, doi: 10.1101/2024.02.23.581737 (2024). (A01, B08, C01, C02)

Karakaya E, Gleichauf L, Schöbel L, Hassan A, Soufivand AA, Tessmar J, Budday S,  Boccaccini AR, Detsch R. Engineering peptide-modified alginate-based bioinks with cell-adhesive properties for biofabrication. RSC Adv. doi: 10.1039/D3RA08394B. (2024). (B06, A02, A01, B09)

Koeck KS, Trossmann VT, Scheibel T. 3D-Printed and Recombinant Spider Silk Particle Reinforced Collagen Composite Scaffolds for Soft Tissue Engineering. Adv. Funct. Mater. doi: 10.1002/adfm.202407760 (2024). (A08, C01)

Krolinski A, Sommer K, Wiesner J, Friedrich O, Vielreicher M. Optimized Method of 3D Scaffold Seeding, CellCultivation, and Monitoring Cell Status for Bone Tissue Engineering. Methods in Molecular Biology doi:10.1007/978-1-0716-3052-5_30 (2024). (Z02)

Lämmerhirt L, Kappelmann‑Fenzl M, Fischer S, Meier P, Staebler S, Kuphal S, Bosserhoff AK. Loss of miR-101-3p in melanoma stabilizes genomic integrity, leading to cell death prevention. Cellular & Molecular Biology Letters, doi: 10.1186/s11658‑024‑00552‑2 (2024). (Z03)

Lamberger Z, Schubert DW, Buechner M, Chicaiza Cabezas N, Schrüfer S, Murenu N, Schaefer N, Lang G. Advanced optical assessment and modeling of extrusion bioprinting. Scientific Reports doi: 10.1038/s41598-024-64039-y (2024). (A07, Z03)

Lutz J, Yu Y, Wolf A-K, Beilhack A, Groll J, Albrecht K. Impact of Surface Functionality on Biodistribution of Gold Nanoparticles in Silkworms. Adv. NanoBiomed Res., doi: 10.1002/anbr.202200146 (2024). (A06, B07, B08)

Reineke B, Paulus I, Löffelsend S, Yu C-H, Hazur J, Röder J, Hauschild S, Boccaccini AR, Groll J, Förster S. On-chip fabrication and in-flow 3D-printing of microgel constructs: from chip to scaffold materials in one integral process. Biofabrication doi:10.1088/1758-5090/ad3318 (2024). (A06, A01, B06, Z03)

Reinhardt D, ter Mors B, Driessen MD, Gutmann M, Faber J, Haug L, Faber A-M, Herrmann A, Hamm P, Lühmann T, Linz C, Meinel L. Visually distinguishing between tumor tissue and healthy tissue within ten minutes using proteolytic probes. Sens. Diagn., doi: 10.1039/d4sd00047a (2024). (B06)

Rindt WD, Krug M, Yamada S, Sennefelder F, Belz L, Cheng WH, Azeem M, Kuric M, Evers M, Leich E, Hartmann TN, Pereira AR, HermannM, Hansmann J, Mussoni C, Stahlhut P, Ahmad T, Yassin MA, Mustafa K, Ebert R, Jundt F. A 3D bioreactor model to study osteocyte differentiation and mechanobiology under perfusion and compressive mechanical loading. Acta Biomaterialia doi: 10.1016/j.actbio.2024.06.041 (2024). (C06, B05)

Roshanbinfar K, Schiffer S, Carls E, Angeloni M, Koleśnik-Gray M, Schruefer S, Schubert DW, Ferrazzi F, Krstić V, Fleischmann BK, Roell W, Engel FB. Electrically Conductive Collagen-PEDOT: PSS Hydrogel Prevents Post-Infarct Cardiac Arrhythmia and Supports hiPSC-Cardiomyocyte Function. Advanced Materials doi: 10.1002/adma.202403642 (2024).  (C01, A07)

Schipka R, Heltmann-Meyer S, Schneidereit D, Friedrich O, Röder J, Boccaccini AR, Schrüfer S, Schubert DW, Horch RE, Bosserhoff AK, Arkudas A, Kengelbach-Weigand A, Schmid R. Characterization of two different alginate-based bioinks and the influence of melanoma growth within. NaturePortfolio, Scientific Reports doi.org/10.1038/s41598-024-63642-3 (2024). (C03, A01, A07, B08, C04, Z03)

Schmid R, Schmidt SK, Schrüfer S, Schubert DW, Heltmann-Meyer S, Schicht M, Paulsen F, Horch RE, Bosserhoff AK, Kengelbach-Weigand A, Arkudas A. A vascularized in vivo melanoma model suitable for metastasis research of different tumor stages using fundamentally different bioinks. Materials Today Bio doi: 10.1016/j.mtbio.2024.101071 (2024). (A07, C03, C04, Z03)

Schneidereit D, Bauer J, Mnuskina S, Nübler S, Cacciani N, Mühlberg A, Kreiss L, Ritter P , Sebastian Schürmann S, Larsson L, Friedrich O. CAS3D: 3D quantitative morphometry on Second Harmonic Generation image volumes from single skeletal muscle fibers. Computers in Biology and Medicine, doi: 10.1016/j.compbiomed.2024.108618 (2024). (B08, Z02)

Sprenger L, Lu H-H, Trippmacher S, Mansfeld U, Milkin P, Ionov L, Papastavrou G, Boccaccini AR, Salehi S. Composite Alginate Dialdehyde-Gelatin (ADA-GEL) Hydrogel Containing Short Ribbon-Shaped Fillers for Skeletal Muscle Tissue Biofabrication. ACS Applied Materials & Interfaces doi: 10.1021/acsami.4c10751 (2024). (B03, B07, A08)

Staebler S, Rottensteiner-Brandl U, El Ahmad Z, Kappelmann-Fenzl M, Arkudas A, Kengelbach-Weigand A, Bosserhoff AK, Schmidt SK. Transcription factor activating enhancer-binding protein 2ε (AP2ε) modulates phenotypic plasticity and progression of malignant melanoma. Cell Death Dis doi: 10.1038/s41419-024-06733-3 (2024). (C03, Z03)

Türker E, Andrade Mier MS, Faber J, Padilla Padilla SJ, Murenu N, Stahlhut P, Lang G, Lamberger Z, Weigelt J, Schaefer N, Tessmar J, Strissel PL, Blunk T, Budday S, Strick R, Villmann C. Breast tumor cell survival and morphology in a brain-like extracellular matrix depends onmatrix composition and mechanical properties. Adv Biol doi: 10.1002/adbi.202400184. (2024) (A02, A07, B09, C02, C05) (COVER IMAGE)

Vaziri AS, Vasheghani-Farahani E, Hosseinzadeh S, Bagheri F, Büchner M, Schubert DW, Boccaccini AR. Genipin-Cross-Linked Silk Fibroin/Alginate Dialdehyde Hydrogel with Tunable Gelation Kinetics, Degradability, and Mechanical Properties: A Potential Candidate for Tissue Regeneration. Biomacromolecules, doi: 10.1021/acs.biomac.3c01203 (2024). (A01, A07)

Wagner JT, Müller-Schmucker SM, Wang W, Arnold P, Uhlig N, Issmail L, Eberlein V, Damm D, Roshanbinfar K, Ensser A, Oltmanns F, Peter AS, Temchura V, Schrödel S, Engel FB, Thirion C, Grunwald T, Wuhrer M, Grimm D, Überla K. Influence of AAV vector tropism on long-term expression and Fc-γ receptor binding of an antibody targeting SARS-CoV-2. Communications Biology, doi: 10.1038/s42003-024-06529-3 (2024). (C01)

Wiessler A-L, Hasenmüller A-S, Fuhl I, Mille C, Cortes Campo O, Reinhard N, Schenk J, Heinze KG, Schäfer N, Specht C, Villmann C. Role of the glycine receptor beta subunit in synaptic localization and pathogenicity in severe startle disease. J Neurosci doi: 10.1523/jneurosci.0837-23.2023 (2024). (C05, Z02, A07)

Wohlrab S, Müller S, Gekle S. Mechanical complexity of living cells can be mapped onto simple homogeneous equivalents. Biomechanics and Modeling in Mechanobiology doi: 10.1016/j.commatsci.2023.112253 (2024). (B07)

Publications 2023

Ahmadi Soufivand A, Faber J, Hinrichsen J, Budday S. Multilayer 3D bioprinting and complex mechanical properties of alginate-gelatin mesostructures. Sci Rep (2023). (B09)

Andrade Mier MS, Dalton PD, Stahlhut P, Bakirci E, Blum R, Villmann C. Primary Glial Cell and Glioblastoma Morphology in Cocultures Depends on Scaffold Design and Hydrogel Composition. Adv Biol (Weinh) doi:10.1002/adbi.202300029  (2023). (B01, C05)

Böhringer D, Bauer A, Moravec I, Bischof L, Kah D, Mark C, Grundy TJ, Görlach E, Neill GMO, Budday S, Strissel P, Strick R, Malandrino A, Mak M, Rausch M, Fabry B. Fiber alignment in 3D collagen networks as a biophysical marker for cell contractility. Matrix Biology doi: 10.1016/j.matbio.2023.11.004 (2023). (A01, B09, C02, C05)

Chayanun S, Soufivand AA, Faber J, Budday S, Lohwongwatana B, Boccaccini AR. Reinforcing tissue‐engineered cartilage: Nano fibrillated cellulose enhances mechanical properties of Alginate Dialdehyde‐Gelatin (ADA‐GEL) hydrogel. Advanced Engineering Materials doi:10.1002/adem.202300641  (2023). (B09)

Czerwinski T, Bischof L, Böhringer D, Kara S, Wittmann E, Winterl A, Gerum R, Nusser G, Wiesinger M, Budday S, Lux A, Voskens C, Fabry B, Mark C. Immune cells employ intermittent integrin-mediated traction forces for 3D migration. bioRxiv doi:10.1101/2023.04.20.537658  (2023). (A01, B09, C02)

Esser TU, Anspach A, Muenzebrock KA, Kah , Schrüfer S, Schenk J, Heinze KG, Schubert DW, Fabry B, Engel FB. Direct 3D-Bioprinting of hiPSC-derived Cardiomyocytes to Generate Functional Cardiac Tissues. Advanced Materials, doi: 10.1002/adma.202305911 (2023). (C01, Z02, A07, A01, C02)

Genc H, Cianciosi A, Lohse R, Stahlhut P, Groll J, Alexiou C, Cicha I, Jungst T. Adjusting Degree of Modification and Composition of gelAGE-Based Hydrogels Improves Long-Term Survival and Function of Primary Human Fibroblasts and Endothelial Cells in 3D Cultures. Biomacromolecules doi:10.1021/acs.biomac.2c01536  (2023). (B02, B09)

Grossbacher G, Bartolf-Kopp M, Gergely C, Bernal PN, Florczak S, de Ruijter M, Rodriguez NG, Groll J, Malda J, Jungst T, Levato R. Volumetric Printing across Melt Electrowritten Scaffolds Fabricates Multi-Material Living Constructs with Tunable Architecture and Mechanics. Adv Mater doi:10.1002/adma.202300756  (2023). (Z01)

Gruhn T, Ortiz-Monsalve C, Müller C, Heid S, Boccaccini AR, Salehi S. Fabrication of hydrogel-based composite fibers and computer simulation of the filler dynamics in the composite flow. Bioengineering. doi:10.3390/bioengineering10040448. (2023) (B03)

Gruhn T, Ortiz-Monsalve C, Salehi S. Structure formation of rod-like fillers in a contraction flow. Physics of Fluids doi:10.1063/5.0143006  (2023). (B03)

Hahn L, Zorn T, Kehrein J, Kielholz T, Ziegler AL, Forster S, Sochor B, Lisitsyna ES, Durandin NA, Laaksonen T, Aseyev V, Sotriffer C, Saalwachter K, Windbergs M, Poppler AC, Luxenhofer R. Unraveling an Alternative Mechanism in Polymer Self-Assemblies: An Order-Order Transition with Unusual Molecular Interactions between Hydrophilic and Hydrophobic Polymer Blocks. ACS Nano doi:10.1021/acsnano.3c00722  (2023). (A03)

Hazur J, Röder J, Czwalinna J, Schubert DW, Boccaccini AR. Pre‐Crosslinking with Hydrogel Microparticles Enhances the Printability of Alginate‐Based Inks. Macromolecular Materials and Engineering doi:10.1002/mame.202200675  (2023). (A01, A07)

Heinritz C, Ng XJ, Scheibel T. Bio‐inspired Protein‐Based and Activatable Adhesion Systems. Advanced Functional Materials doi:10.1002/adfm.202303609  (2023). (A08, C01)

Hosseinabadi HG, Biswas A, Bhusal A, Yousefinejad A, Lall A, Zimmermann W-H, Miri AK, Ionov L. 4D-Printable Photocrosslinkable Polyurethane-Based Inks for Tissue Scaffold and Actuator Applications. Small, doi: 10.1002/smll.202306387 (2023). (A08)

Kahl M, Schneidereit D, Meinert C, Bock N, Hutmacher DW, Friedrich O. A fluorescence-based opto-mechatronic screening module (OMSM) for automated 3D cell culture workflows. Biosensors and Bioelectronics (2023). (B08 (Z02))

Karakaya E, Schobel L, Zhong Y, Hazur J, Heid S, Forster L, Tessmar J, Boccaccini AR, Detsch R. How to Determine a Suitable Alginate for Biofabrication Approaches using an Extensive Alginate Library?. Biomacromolecules doi:10.1021/acs.biomac.2c01282  (2023). (B06, A02, A01)

Khadem E, Kharaziha M, Salehi S. Colorimetric pH-responsive and hemostatic hydrogel-based bioadhesives containing functionalized silver nanoparticles. Mater Today Bio (2023). (B03)

Kitana W, Levario-Diaz V, Cavalcanti-Adam EA, Ionov L. Biofabrication of Composite Bioink-Nanofiber Constructs: Effect of Rheological Properties of Bioinks on 3D (Bio)Printing and Cells Interaction with Aligned Touch Spun Nanofibers. Adv. Healthcare Mater., doi: 10.1002/adhm.202303343 (2023). (A08)

Kockelmann J, Zentel R, Nuhn L. Post‐Polymerization Modifications to Prepare Biomedical Nanocarriers with Varying Internal Structures, their Properties and Impact on Protein Corona Formation. Macromolecular Chemistry and Physics doi:10.1002/macp.202300199  (2023). (B05)

Lamberger Z, Zainuddin S, Scheibel T, Lang G. Polymeric Janus Fibers. Chempluschem (2023). (A07, C01)

Martinez-Sanchez LDC, Ngo PA, Pradhan R, Becker LS, Boehringer D, Soteriou D, Kubankova M, Schweitzer C, Koch T, Thonn V, Erkert L, Stolzer I, Gunther C, Becker C, Weigmann B, Klewer M, Daniel C, Amann K, Tenzer S, Atreya R, Bergo M, Brakebusch C, Watson AJM, Guck J, Fabry B, Atreya I, Neurath MF, Lopez-Posadas R. Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation. Gut (2023). (A01)

Mühlberg A, Ritter P, Langer S, Goossens C, Nübler S, Schneidereit D, Taubmann O, Denzinger F, Nörenberg D, Haug M, Schürmann S, Horstmeyer R, Maier AK, Goldmann WH, Friedrich O, Kreiss L. SEMPAI: a Self-Enhancing Multi-Photon Artificial Intelligence for Prior-Informed Assessment of Muscle Function and Pathology. Adv Sci., doi: 10.1002/advs.202206319 (2023). (Z02)

Mueller JPJ, Dobosz M, O’Brien N, Abdoush N, Giusti AM, Lechmann M, Osl F, Wolf A-K, Arellano-Viera E, Shaikh H, Sauer M, Rosenwald A, Herting F, Umaña P, Colombetti S, Pöschinger T, Beilhack A. ROCKETS – a novel one-for-all toolbox for light sheet microscopy in drug discovery. Frontiers in Immunology 14 (2023). (B08)

Mut J, Altmann S, Reising S, Meissner-Weigl J, Driessen MD, Ebert R, Seibel J. SiaNAl can be efficiently incorporated in glycoproteins of human mesenchymal stromal cells by metabolic glycoengineering. ACS Biomater Sci Eng doi:10.1021/acsbiomaterials.2c01534  (2023). (B05)

Pantawane S, Mueller S, Gekle S. Effect of particle insertion on Poly(3-hexylthiophene) brush’s π-π stacking. Computational Materials Science 226 (2023). (B07)

Polley C, Distler T, Scheufler C, Detsch R, Lund H, Springer A, Schneidereit D, Friedrich O, Boccaccini AR, Seitz H. 3D printing of piezoelectric and bioactive barium titanate-bioactive glass scaffolds for bone tissue engineering. Materials Today Bio doi:10.1016/j.mtbio.2023.100719  (2023). (Z02)

Rederer A, Rose V, Krüger R, Schmittutz L, Swierzy I, Fischer L, Thievessen I, Bauer J , Friedrich O , Schiffer M, Müller-Deile J. Partner, Neighbor, Housekeeper and Dimension: 3D versus 2D Glomerular Co-Cultures Reveal Drawbacks of Currently Used Cell Culture Models. International Journal of Molecular Science doi: 10.3390/ijms241210384 (2023). (C06, Z02)

Rockel AF, Wagner N, Spenger P, Ergun S, Worsdorfer P, Neuro-mesodermal assembloids recapitulate aspects of peripheral nervous system development in vitro, Stem Cell Reports doi:10.1016/j.stemcr.2023.03.012  (2023). (B04)

Roshanbinfar K, Kolesnik-Gray M, Angeloni M, Schruefer S, Fiedler M, Schubert DW, Ferrazzi F, Krstic V, Engel FB. Collagen Hydrogel Containing Polyethylenimine-Gold Nanoparticles for Drug Release and Enhanced Beating Properties of Engineered Cardiac Tissues. Adv Healthc Mater doi:10.1002/adhm.202202408  (2023) e2202408. (C01)

Schaefer N, Andrade Mier MS, Sonnleitner D, Murenu N, Ng XJ, Lamberger Z, Buechner M, Trossmann VT, Schubert DW, Scheibel T, Lang G. Rheological and Biological Impact of Printable PCL-Fibers as Reinforcing Fillers in Cell-Laden Spider-Silk Bio-Inks, Small Methods doi:10.1002/smtd.202201717  (2023) e2201717. (A07, C01, C05)

Schöbel L, Karakaya E, Detsch R, Boccaccini AR. Preparation of Compact Alginate Films for 2D in vitro Studies: Challenges and Strategies for Improvement, Materials Letters doi:10.1016/j.matlet.2023.134103  (2023). (A01, B06)

Schorzmann, Gerstl, Tan, Sprenger, Lu, Taumann, Wimmer, Boccaccini, Salehi-Müller, Döpper. Materials Screening Methodology for additive manufacturing in bioreactor technology. (2023) International Solid Freeform Fabrication Symposium on 15th August 2023. (B03)

Schulik J, Salehi S, Boccaccini AR, Schrüfer S, Schubert DW, Arkudas A, Kengelbach-Weigand A, Horch RE, Schmid R. Comparison of the Behavior of 3D-Printed Endothelial Cells in Different Bioinks. Bioengineering (2023). (C03, A07, C04, B03)

Sörgel CA, Cai A, Schmid R, Horch RE. Perspectives on the Current State of Bioprinted Skin Substitutes for Wound Healing. Biomedicines, doi: 10.3390/biomedicines11102678 (2023). (C03, C04)

Sommer KP, Krolinski A, Mirkhalaf M, Zreiqat H, Friedrich O, Vielreicher M. Protocol for Cell Colonization and Comprehensive Monitoring of Osteogenic Differentiation in 3D Scaffolds Using Biochemical Assays and Multiphoton Imaging. International Journal of Molecular Sciences (2023). (B08)

Soufivand AA, Budday S. Predicting the hyperelastic properties of alginate-gelatin hydrogels and 3D bioprinted mesostructures. Scientific Reports, doi: 10.1038/s41598-023-48711-3 (2023). (B09)

Sternstein C, Bohm TM, Fink J, Meyr J, Ludemann M, Krug M, Kriukov K, Gurdap CO, Sezgin E, Ebert R, Seibel J. Development of an Effective Functional Lipid Anchor for Membranes (FLAME) for the Bioorthogonal Modification of the Lipid Bilayer of Mesenchymal Stromal Cells. Bioconjug Chem doi:10.1021/acs.bioconjchem.3c00091  (2023). (B05)

Ter Mors B, Spieler V, Merino Asumendi E, Gantert B, Luhmann T, Meinel L. Bioresponsive Cytokine Delivery Responding to Matrix Metalloproteinases. ACS Biomater Sci Eng doi:10.1021/acsbiomaterials.2c01320  (2023). (B06)

Tesler AB, Kolle S, Prado LH, Thievessen I, Böhringer D, Backholm M, Karunakaran B, Nurmi HA, Latikka M, Fischer L, Stafslien S, Cenev ZM, Timonen JVI, Bruns M, Mazare A, Lohbauer U, Virtanen S, Fabry B, Schmuki P, Ras RHA, Aizenberg J, Goldmann WH. Long-term stability of aerophilic metallic surfaces underwater. Nature Materials doi: 10.1038/s41563-023-01670-6 (2023). (A01, C02)

Trossmann VT, Lentz S, Scheibel T. Factors Influencing Properties of Spider Silk Coatings and Their Interactions within a Biological Environment. Journal of Functional Biomaterials (2023). (A08, C01)

Trossmann VT, Scheibel T. Design of Recombinant Spider Silk Proteins for Cell Type Specific Binding. Adv Healthc Mater (2023) e2202660. (C01)

Trossmann VT, Scheibel T. Designte Spinnenseidenmaterialien für zellspezifische Interaktionen. Biospektrum doi: 10.1007/s12268-023-2026-4 (2023). (C01)

Unalan I, Schruefer S, Schubert DW, Boccaccini AR. 3D-Printed Multifunctional Hydrogels with Phytotherapeutic Properties: Development of Essential Oil-Incorporated ALG-XAN Hydrogels for Wound Healing Applications. ACS Biomater Sci Eng doi:10.1021/acsbiomaterials.3c00406  (2023). (A07)

Vaghela R, Arkudas A, Gage D, Korner C, von Horsten S, Salehi S, Horch RE, Hessenauer M. A Novel Window into Angiogenesis-Intravital Microscopy in the AV-Loop-Model. Cells (2023). (B03, C03, C04)

Wörsdörfer P, Ergün S. “Organoids”: Insights from the First Issues. Organoids (2023) 79-81. (B04)

Wolkersdorfer AM, Jugovic I, Scheller L, Gutmann M, Hahn L, Diessner J, Luhmann T, Meinel L. PEGylation of Human Vascular Endothelial Growth Factor. ACS Biomater Sci Eng doi:10.1021/acsbiomaterials.3c00253 (2023). (B06)

Publications 2022

An R, Strissel PL, Al-Abboodi M, Robering JW, Supachai R, Eckstein M, Peddi A, Hauck T, Bäuerle T, Boccaccini AR, Youssef A, Sun J, Strick R, Horch RE, Boos AM, Kengelbach-Weigand A, An Innovative Arteriovenous (AV) Loop Breast Cancer Model Tailored for Cancer Research, Bioengineering 9(7) (2022). (C03, B01, A01)

Apsite I, Salehi S, Ionov L, Materials for Smart Soft Actuator Systems, Chem Rev 122(1) (2022) 1349-1415. (B03)

Bednarzig V, Schrufer S, Schneider TC, Schubert DW, Detsch R, Boccaccini AR, Improved 3D Printing and Cell Biology Characterization of Inorganic-Filler Containing Alginate-Based Composites for Bone Regeneration: Particle Shape and Effective Surface Area Are the Dominant Factors for Printing Performance, Int J Mol Sci 23(9) (2022). (A07)

Beudert M, Gutmann M, Luhmann T, Meinel L, Fibrin Sealants: Challenges and Solutions, ACS Biomater Sci Eng doi:10.1021/acsbiomaterials.1c01437  (2022). (A03)

Beudert M, Hahn L, Horn AHC, Hauptstein N, Sticht H, Meinel L, Luxenhofer R, Gutmann M, Luhmann T, Merging bioresponsive release of insulin-like growth factor I with 3D printable thermogelling hydrogels, J Control Release 347 (2022) 115-126 (A03)

Bider F, Karakaya E, Mohn D, Aldo R, Boccaccini, Advantages of nanoscale bioactive glass as inorganic filler in alginate hydrogels for drug delivery and biofabrication, European Journal of Materials 2(1) (2022) 33-53. (B03)

Brand JS, Forster L, Bock T, Stahlhut P, Tessmar J, Groll J, Albrecht K, Covalently Cross-Linked Pig Gastric Mucin Hydrogels Prepared by Radical-Based Chain-Growth and Thiol-ene Mechanisms, Macromol Biosci 22(4) (2022) e2100274. (B07, A02, A06)

Ergün S, Wörsdörfer P, Organoids, Assembloids and Embryoids: New Avenues for Developmental Biology, Disease Modeling, Drug Testing and Toxicity Assessment without Animal Experimentation, Organoids 1(1) (2022) 37-40.

Ertekin O, Monavari M, Kruger R, Fuentes-Chandia M, Parma B, Letort G, Tripal P, Boccaccini AR, Bosserhoff AK, Ceppi P, Kappelmann-Fenzl M, Leal-Egana A, 3D hydrogel-based microcapsules as an in vitro model to study tumorigenicity, cell migration and drug resistance, Acta Biomater 142 (2022) 208-220. (C03)

Faber J, Hinrichsen J, Greiner A, Reiter N, Budday S, Tissue-Scale Biomechanical Testing of Brain Tissue for the Calibration of Nonlinear Material Models, Curr Protoc 2(4) (2022) e381. (B09)

Fischer L, Nosratlo M, Hast K, Karakaya E, Strohlein N, Esser T, Gerum RC, Richter S, Engel FB, Detsch R, Fabry B, Thievessen I, Calcium supplementation of bioinks reduces shear stress-induced cell damage during bioprinting, Biofabrication doi:10.1088/1758-5090/ac84af (2022). (A01, B06, C01, C02)

Gerum R, Mirzahossein E, Eroles M, Elsterer J, Mainka A, Bauer A, Sonntag S, Winterl A, Bartl J, Fischer L, Abuhattum S, Goswami R, Girardo S, Guck J, Schrufer S, Strohlein N, Nosratlo M, Herrmann H, Schultheis D, Rico F, Muller SJ, Gekle S, Fabry B, Viscoelastic properties of suspended cells measured with shear flow deformation cytometry, Elife 11 (2022). (A01, A07, B07)

Haag H, Sonnleitner D, Lang G, Dalton PD, Melt electrowriting to produce microfiber fragments, Polymers for Advanced Technologies doi:10.1002/pat.5641  (2022). (A04, A07)

Hauptstein J, Forster L, Nadernezhad A, Horder H, Stahlhut P, Groll J, Blunk T, Tessmar J, Bioink Platform Utilizing Dual-Stage Crosslinking of Hyaluronic Acid Tailored for Chondrogenic Differentiation of Mesenchymal Stromal Cells, Macromol Biosci 22(2) (2022) e2100331. (A02, A06, B02, C02)

Hauptstein J, Forster L, Nadernezhad A, Groll J, Teßmar J, Blunk T, Tethered TGF-β1 in a Hyaluronic Acid-Based Bioink for Bioprinting Cartilaginous Tissues, International Journal of Molecular Sciences 23(2) (2022). (A02, A06, B02)

Heid S, Becker K, Byun J, Biermann I, Neščáková Z, Zhu H, Groll J, Boccaccini AR, Bioprinting with bioactive alginate dialdehyde-gelatin (ADA-GEL) composite bioinks: Time-dependent in-situ crosslinking via addition of calcium-silicate particles tunes in vitro stability of 3D bioprinted constructs, Bioprinting doi:10.1016/j.bprint.2022.e00200  (2022). (B03, A01, A06)

Hu C, Ahmad T, Haider MS, Hahn L, Stahlhut P, Groll J, Luxenhofer R, A thermogelling organic-inorganic hybrid hydrogel with excellent printability, shape fidelity and cytocompatibility for 3D bioprinting, Biofabrication 14(2) (2022). (A03)

Janzen D, Bakirci E, Faber J, Mier MA, Hauptstein J, Pal A, Forster L, Hazur J, Boccaccini AR, Detsch R, Tessmar J, Budday S, Blunk T, Dalton PD, Villmann C, Reinforced Hyaluronic acid-based Matrices promote 3D Neuronal Network Formation, Adv Healthc Mater doi:10.1002/adhm.202201826  (2022) e2201826. (A01, A02, B06, B09, B01/C05)

Kara A, Distler T, Polley C, Schneidereit D, Seitz H, Friedrich O, Tihminlioglu F, Boccaccini AR, 3D printed gelatin/decellularized bone composite scaffolds for bone tissue engineering: Fabrication, characterization and cytocompatibility study, Materials Today Bio 15 (2022). (B08, Z02)

Karakaya E, Bider F, Frank A, Teßmar J, Schöbel L, Forster L, Schrüfer S, Schmidt H-W, Schubert DW, Blaeser A, Boccaccini AR, Detsch R, Targeted Printing of Cells: Evaluation of ADA-PEG Bioinks for Drop on Demand Approaches, Gels 8(4) (2022). (B06, A02, A04, A07)

Kitana W, Apsite I, Hazur J, Boccaccini AR, Ionov L, 4D Biofabrication of T‐Shaped Vascular Bifurcation, Advanced Materials Technologies doi:10.1002/admt.202200429  (2022). (A01, A08)

Kleefeldt F, Upcin B, Bommel H, Schulz C, Eckner G, Allmanritter J, Bauer J, Braunger B, Rueckschloss U, Ergun S, Bone marrow-independent adventitial macrophage progenitor cells contribute to angiogenesis, Cell Death Dis 13(3) (2022) 220. (B04)

Kratzer S, Arkudas A, Himmler M, Schubert DW, Schneidereit D, Bauer J, Friedrich O, Horch RE, Cai A, Vascularization of Poly-epsilon-Caprolactone-Collagen I-Nanofibers with or without Sacrificial Fibers in the Neurotized Arteriovenous Loop Model, Cells 11(23) (2022). (Z02)

Lang G, Sonnleitner D, Biomimetic Protein‑based Elastomers – Processing and Properties of regenerated B. mori silk and recombinant spider silk fibers, Royal Society of Chemistry (2022). (A07)

Lechner A, Trossmann VT, Scheibel T, Impact of Cell Loading of Recombinant Spider Silk Based Bioinks on Gelation and Printability, Macromol Biosci 22(3) (2022) e2100390. (C01)

Lentz S, Trossmann VT, Borkner CB, Beyersdorfer V, Rottmar M, Scheibel T, Structure-Property Relationship Based on the Amino Acid Composition of Recombinant Spider Silk Proteins for Potential Biomedical Applications, ACS Appl Mater Interfaces doi:10.1021/acsami.2c09590  (2022). (C01)

Lentz S, Trossmann VT, Scheibel T, Selective Topography Directed Cell Adhesion on Spider Silk Surfaces, Advanced Materials Interfaces doi:10.1002/admi.202201936  (2022). (C01)

Mair V, Paulus I, Groll J, Ryma M, Freeform printing of thermoresponsive poly(2-cyclopropyl-oxazoline) as cytocompatible and on-demand dissolving template of hollow channel networks in cell-laden hydrogels, Biofabrication doi:10.1088/1758-5090/ac57a7  (2022). (B02)

Mehnert M, Faber J, Hossain M, Chester SA, Steinmann P, Experimental and numerical investigation of the electro-mechanical response of particle filled elastomers – Part I: Experimental investigations, European Journal of Mechanics – A/Solids 96 (2022). (B09)

Mehnert M, Faber J, Hossain M, Chester SA, Steinmann P, Experimental and numerical investigations of the electro-mechanical response of particle filled elastomers—Part II: Continuum modeling approach, European Journal of Mechanics – A/Solids 96 (2022). (B09)

Nadernezhad A, Groll J, Machine Learning Reveals a General Understanding of Printability in Formulations Based on Rheology Additives, Adv Sci (Weinh) doi:10.1002/advs.202202638  (2022) e2202638. (B04, A06)

Neubauer VJ, Hüter F, Wittmann J, Trossmann VT, Kleinschrodt C, Alber-Laukant B, Rieg F, Scheibel T, Flow Simulation and Gradient Printing of Fluorapatite- and Cell-Loaded Recombinant Spider Silk Hydrogels, Biomolecules 12(10) (2022). (C01)

Peters G, Jakubass B, Weidenfeller K, Kniesburges S, Bohringer D, Wendler O, Mueller SK, Gostian AO, Berry DA, Dollinger M, Semmler M, Synthetic mucus for an ex vivo phonation setup: Creation, application, and effect on excised porcine larynges, J Acoust Soc Am 152(6) (2022) 3245. (A01)

Pien N, Bartolf‐Kopp M, Parmentier L, Delaey J, De Vos L, Mantovani D, Van Vlierberghe S, Dubruel P, Jungst T, Melt Electrowriting of a Photo‐Crosslinkable Poly( ε ‐Caprolactone)‐Based Material into Tubular Constructs with Predefined Architecture and Tunable Mechanical Properties, Macromolecular Materials and Engineering doi:10.1002/mame.202200097  (2022). (Z01)

Ritter P, Cai A, Reischl B, Fiedler M, Prol G, Frie B, Kretzschmar E, Michael M, Hartmann K, Lesko C, Salti H, Arkudas A, Horch R, Paulsen F, Friedrich O, Haug M, MyoBio: An automated bioreactor system technology for standardized perfusion-decellularization of whole skeletal muscle, IEEE Trans Biomed Eng PP (2022). (B08, C04)

Ryma M, Genc H, Nadernezhad A, Paulus I, Schneidereit D, Friedrich O, Andelovic K, Lyer S, Alexiou C, Cicha I, Groll J, A print-and-fuse Strategy for Sacrificial Filaments Enables Biomimetically Structured Perfusable Microvascular Networks with Functional Endothelium Inside 3D Hydrogels, Adv Mater doi:10.1002/adma.202200653  (2022) e2200653. (B02, B08, A06)

Schaefer N, Harvey RJ, Villmann C, Startle Disease: New Molecular Insights into an Old Neurological Disorder, Neuroscientist doi:10.1177/10738584221104724  (2022) 10738584221104724. (B01, A07, C05)

Schmid R, Schmidt SK, Detsch R, Horder H, Blunk T, Schrufer S, Schubert DW, Fischer L, Thievessen I, Heltmann-Meyer S, Steiner D, Schneidereit D, Friedrich O, Gruneboom A, Amouei H, Wajant H, Horch RE, Bosserhoff AK, Arkudas A, Kengelbach-Weigand A, A New Printable Alginate/Hyaluronic Acid/Gelatin Hydrogel Suitable for Biofabrication of In Vitro and In Vivo Metastatic Melanoma Models, Advanced Functional Materials 32(2) (2022). (C03, A01, A07, B06, B08, C02, C04)

Schubert DW, Simple Model for the Spreading of Inks in Bioprinting-Revealing Relevant Scaling Laws-Part I Theory, Macromolecular Theory and Simulations 31(1) (2022). (A07)

Sivakumar S, Schmid R, Wieland A, Strissel PL, Strick R, Fischer L, Thievessen I, Kataev E, Arkudas A, Horch RE, Schubert DW, Kengelbach‐Weigand A, Role of Fiber Thickness and Surface Treatment of Electrospun Polycaprolactone Matrices on the Growth of Different Breast Cancer‐Associated Cells, Advanced Materials Interfaces doi:10.1002/admi.202101808  (2022). (B01,  B06,  C03)

Sörgel CA, Schmid R, Stadelmann N, Weisbach V, Distel L, Horch RE, Kengelbach-Weigand A, IGF-I and Hyaluronic Acid Mitigate the Negative Effect of Irradiation on Human Skin Keratinocytes, Cancers 14(3) (2022). (C03, C04)

Sporrer M, Kah D, Gerum RC, Reischl B, Huraskin D, Dessalles CA, Schneider W, Goldmann WH, Herrmann H, Thievessen I, Clemen CS, Friedrich O, Hashemolhosseini S, Schroder R, Fabry B, The desmin mutation R349P increases contractility and fragility of stem cell-generated muscle micro-tissues, Neuropathol Appl Neurobiol 48(3) (2022) e12784. (A01, B08, C02)

Steiner D, Reinhardt L, Fischer L, Popp V, Korner C, Geppert CI, Bauerle T, Horch RE, Arkudas A, Impact of Endothelial Progenitor Cells in the Vascularization of Osteogenic Scaffolds, Cells 11(6) (2022). (C04)

Trossmann VT, Heltmann-Meyer S, Amouei H, Wajant H, Horch RE, Steiner D, Scheibel T, Recombinant Spider Silk Bioinks for Continuous Protein Release by Encapsulated Producer Cells, Biomacromolecules doi:10.1021/acs.biomac.2c00971  (2022). (C01, C04)

Trossmann VT, Scheibel T, Design of Recombinant Spider Silk Proteins for Cell Type Specific Binding, Adv Healthc Mater doi:10.1002/adhm.202202660  e2202660 (2022). (C01)

Vaghela R, Arkudas A, Gage D, Korner C, von Horsten S, Salehi S, Horch RE, Hessenauer M, Microvascular development in the rat arteriovenous loop model in vivo-A step by step intravital microscopy analysis, J Biomed Mater Res A doi:10.1002/jbm.a.37395 (2022). (B03, C04)

Publications 2021

Altmann S, Mut J, Wolf N, Meissner-Weigl J, Rudert M, Jakob F, Gutmann M, Luhmann T, Seibel J, Ebert R, Metabolic Glycoengineering in hMSC-TERT as a Model for Skeletal Precursors by Using Modified Azide/Alkyne Monosaccharides, Int. J. Mol. Sci. 22(6) (2021) 2820. (B05, A03)

Apsite I, Salehi S, Ionov L, Materials for Smart Soft Actuator Systems, Chem Rev doi:10.1021/acs.chemrev.1c00453  (2021). (B03)

Bächer C, Graessel K, Gekle S, Rayleigh–Plateau instability of anisotropic interfaces. Part 2. Limited instability of elastic interfaces, J. Fluid Mech. 910 (2021) A47. (B07)

Bauer A, Prechova M, Fischer L, Thievessen I, Gregor M, Fabry B, pyTFM: A tool for traction force and monolayer stress microscopy, PLoS Comput Biol 17(6) (2021) e1008364. (A01, B06)

Bednarzig V, Karakaya E, Egana AL, Teßmar J, Boccaccini AR, Detsch R, Advanced ADA-GEL bioink for bioprinted artificial cancer models, Bioprinting doi:10.1016/j.bprint.2021.e00145  (2021) 00145. (B06, A01, A02)

Blum C, Taskin MB, Shan J, Schilling T, Schlegelmilch K, Tessmar J, Groll J, Appreciating the First Line of the Human Innate Immune Defense: A Strategy to Model and Alleviate the Neutrophil Elastase-Mediated Attack toward Bioactivated Biomaterials, Small 17(13) (2021) 2007551. (A06, A02)

Brand JS, Forster L, Bock T, Stahlhut P, Tessmar J, Groll J, Albrecht K, Covalently Crosslinked Pig Gastric Mucin Hydrogels Prepared by Radical-based Chain-Growth and Thiol-ene Mechanisms, Macromol Biosci doi:10.1002/mabi.202100274  (2021) e2100274. (B07, A02, A06)

Cai FF, Heid S, Boccaccini AR, Potential of Laponite(R) incorporated oxidized alginate-gelatin (ADA-GEL) composite hydrogels for extrusion-based 3D printing, J. Biomed. Mater. Res., Part B doi:10.1002/jbm.b.34771  (2021) 1 – 15. (B03)

Constante G, Apsite I, Alkhamis H, Dulle M, Schwarzer M, Caspari A, Synytska A, Salehi S, Ionov L, 4D Biofabrication Using a Combination of 3D Printing and Melt-Electrowriting of Shape-Morphing Polymers, ACS Appl Mater Interfaces 13(11) (2021) 12767-12776. (B03)

Distler T, Kretzschmar L, Schneidereit D, Girardo S, Goswami R, Friedrich O, Detsch R, Guck J, Boccaccini AR, Budday S, Mechanical properties of cell- and microgel bead-laden oxidized alginate-gelatin hydrogels, Biomater. Sci. 9(8) (2021) 3051-3068. (B06, B08)

Distler T, Polley C, Shi F, Schneidereit D, Ashton MD, Friedrich O, Kolb JF, Hardy JG, Detsch R, Seitz H, Boccaccini AR, Electrically Conductive and 3D-Printable Oxidized Alginate-Gelatin Polypyrrole:PSS Hydrogels for Tissue Engineering, Adv Healthc Mater 10 (2021) 2001876. (B08)

Dogan L, Scheuring R, Wagner N, Ueda Y, Wörsdörfer P, Groll J, Ergün S, Human iPSC-derived mesodermal progenitor cells preserve their vasculogenesis potential after extrusion and form hierarchically organized blood vessels, Biofabrication 13(4)  (2021). (B04)

Esser TU, Trossmann VT, Lentz S, Engel FB, Scheibel T, Designing of spider silk proteins for hiPSC-based cardiac tissue engineering, Mater Today Bio doi:10.1016/j.mtbio.2021.100114  (2021). (C01)

Farasatkia A, Kharaziha M, Ashrafizadeh F, Salehi S, Transparent silk/gelatin methacrylate (GelMA) fibrillar film for corneal regeneration, Mater Sci Eng C Mater Biol Appl 120 (2021) 111744. (B03)

Fischhaber N, Faber J, Bakirci E, Dalton PD, Budday S, Villmann C, Schaefer N, Spinal Cord Neuronal Network Formation in a 3D Printed Reinforced Matrix-A Model System to Study Disease Mechanisms, Adv Healthc Mater doi:10.1002/adhm.202100830  (2021) e2100830. (B01, Z01)

Förster S, Groll J, Reineke B, Hauschild S, Paulus I, Hazur J, Vollmer M, Tamgüney G, Boccacini A, On-chip-fabrication-and-in-flow-3d-printing-of-cell-laden-microgel-constructs-from-chip-to-scaffold-materials-in-one-integral-process, doi:10.26434/chemrxiv.14564508.v1  (2021). (A06)

Friedrich RP, Cicha I, Alexiou C, Iron Oxide Nanoparticles in Regenerative Medicine and Tissue Engineering, Nanomaterials 11(9) (2021). (B02)

Fuentes-Chandia M, Vierling A, Kappelmann-Fenzl M, Monavari M, Letort G, Hone L, Parma B, Antara SK, Ertekin O, Palmisano R, Dong M, Bopple K, Boccaccini AR, Ceppi P, Bosserhoff AK, Leal-Egana A, 3D Spheroids Versus 3D Tumor-Like Microcapsules: Confinement and Mechanical Stress May Lead to the Expression of Malignant Responses in Cancer Cells, Adv. Biol. doi:10.1002/adbi.202000349  (2021) 2000349. (C03, A01)

Genc H, Hazur J, Karakaya E, Dietel B, Bider F, Groll J, Alexiou C, Boccaccini AR, Detsch R, Cicha I, Differential Responses to Bioink-Induced Oxidative Stress in Endothelial Cells and Fibroblasts, Int. J. Mol. Sci. 22(5) (2021) 2358. (B02, A01, B06)

Hahn L, Beudert M, Gutmann M, Kessler L, Stahlhut P, Fischer L, Karakaya E, Lorson T, Thievessen I, Detsch R, Luhmann T, Luxenhofer R, From Thermogelling Hydrogels toward Functional Bioinks: Controlled Modification and Cytocompatible Crosslinking, Macromol. Biosci. doi:10.1002/mabi.202100122  (2021) e2100122. (A03, B06)

Hahn L, Keßler L, Polzin L, Fritze L, Forster S, Helten H, Luxenhofer R, ABA Type Amphiphiles with Poly(2‐benzhydryl‐2‐oxazine) Moieties: Synthesis, Characterization and Inverse Thermogelation, Macromol. Chem. Phys. doi:10.1002/macp.202100114  (2021). (A03)

Hahn L, Karakaya E, Zorn T, Sochor B, Maier M, Stahlhut P, Forster S, Fischer K, Seiffert S, Poppler AC, Detsch R, Luxenhofer R, An Inverse Thermogelling Bioink Based on an ABA-Type Poly(2-oxazoline) Amphiphile, Biomacromolecules doi:10.1021/acs.biomac.1c00427  (2021). (A03, B06)

Hahn L, Zorn T, Kehrein J, Kielholz T, Ziegler A-L, Forster S, Sochor B, Lisitsyna ES, Durandin N, Laaksonen T, Aseyev V, Sotriffer C, Windbergs M, Pöppler A-C, Luxenhofer R, Unravelling-a-novel-mechanism-in-polymer-self-assemblies-an-order-order-transition-based-on-molecular-interactions-between-hydrophilic-and-hydrophobic-polymer-blocks, doi:10.33774/chemrxiv-2021-mjd8n-v2  (2021). (A03)

Haider MS, Ahmad T, Yang M, Hu C, Hahn L, Stahlhut P, Groll J, Luxenhofer R, Tuning the Thermogelation and Rheology of Poly(2-Oxazoline)/Poly(2-Oxazine)s Based Thermosensitive Hydrogels for 3D Bioprinting, Gels 7(3) (2021). (A03)

Hasselmann S, Hahn L, Lorson T, Schatzlein E, Sebastien I, Beudert M, Luhmann T, Neubauer JC, Sextl G, Luxenhofer R, Heinrich D, Freeform direct laser writing of versatile topological 3D scaffolds enabled by intrinsic support hydrogel, Mater Horiz doi:10.1039/d1mh00925g (2021). (A03)

Hauptstein J, Forster L, Nadernezhad A, Horder H, Stahlhut P, Groll J, Blunk T, Teßmar J, Bioink Platform Utilizing Dual-stage Crosslinking of Hyaluronic Acid Tailored for Chondrogenic Differentiation of Mesenchymal Stromal Cells, Macromolecular Bioscience n/a(n/a)  2100331. (A02, A06, B02, C02)

Hazur J, Endrizzi N, Schubert DW, Boccaccini AR, Fabry B, Stress relaxation amplitude of hydrogels determines migration, proliferation, and morphology of cells in 3-D doi:10.1101/2021.07.08.451608  (2021). (A01, A07, C02)

Heltmann-Meyer S, Steiner D, Muller C, Schneidereit D, Friedrich O, Salehi S, Engel FB, Arkudas A, Horch RE, Gelatin methacryloyl is a slow degrading material allowing vascularization and long-term usein vivo, Biomed Mater 16(6) (2021). (B03, B08, C01, C04)

Hesselbarth R, Esser TU, Roshanbinfar K, Schrufer S, Schubert DW, Engel FB, CHIR99021 Promotes hiPSC-Derived Cardiomyocyte Proliferation in Engineered 3D Microtissues, Adv Healthc Mater doi:10.1002/adhm.202100926  (2021) e2100926. (C01, A07)

Hessenauer MET, Vaghela R, Korner C, von Horsten S, Pobel C, Gage D, Muller C, Salehi S, Horch RE, Arkudas A, Watching the vessels grow – establishment of intravital microscopy in the AV-loop rat model, Tissue Eng Part C Methods doi:10.1089/ten.TEC.2021.0024  (2021). (C04, B03)

Horder H, Guaza Lasheras M, Grummel N, Nadernezhad A, Herbig J, Ergun S, Tessmar J, Groll J, Fabry B, Bauer-Kreisel P, Blunk T, Bioprinting and Differentiation of Adipose-Derived Stromal Cell Spheroids for a 3D Breast Cancer-Adipose Tissue Model, Cells 10(4) (2021) 803. (C02, A02, B02, B04)

Horvat S, Yu Y, Manz H, Keller T, Beilhack A, Groll J, Albrecht K, Nanogels as Antifungal‐Drug Delivery System Against Aspergillus Fumigatus, Advanced NanoBiomed Research 1(5) (2021) 2000060. (B07, B08)

Hu C, Hahn L, Yang MS, Altmann A, Stahlhut P, Groll J, Luxenhofer R, Improving printability of a thermoresponsive hydrogel biomaterial ink by nanoclay addition, J. Mater. Sci. 56(1) (2021) 691-705. (A03)

Hu C, Haider MS, Hahn L, Yang M, Luxenhofer R, Development of a 3D printable and highly stretchable ternary organic-inorganic nanocomposite hydrogel, J Mater Chem B 9(22) (2021) 4535-4545. (A03)

Kah D, Winterl A, Přechová M, Schöler U, Schneider W, Friedrich O, Gregor M, Fabry B, A low-cost uniaxial cell stretcher for six parallel wells, HardwareX 9 (2021). (A01, B08, C02)

Kahl M, Schneidereit D, Bock N, Friedrich O, Hutmacher DW, Meinert C, MechAnalyze – an algorithm for standardization and automation of compression test analysis, Tissue Eng Part C Methods doi:10.1089/ten.TEC.2021.0170  (2021). (B08)

Kappelmann-Fenzl M, Schmidt SK, Fischer S, Schmid R, Lammerhirt L, Fischer L, Schrufer S, Thievessen I, Schubert DW, Matthies A, Detsch R, Boccaccini AR, Arkudas A, Kengelbach-Weigand A, Bosserhoff AK, Molecular Changes Induced in Melanoma by Cell Culturing in 3D Alginate Hydrogels, Cancers (Basel) 13(16) (2021). (C03, A01, A07, B06)

Kim J, Bakirci E, O’Neill KL, Hrynevich A, Dalton PD, Fiber Bridging during Melt Electrowriting of Poly(ε‐Caprolactone) and the Influence of Fiber Diameter and Wall Height, Macromol. Mater. Eng. 306(3) (2021). (B01)

Lechner A, Trossmann VT, Scheibel T, Impact of Cell Loading of Recombinant Spider Silk Based Bioinks on Gelation and Printability, Macromol Biosci doi:10.1002/mabi.202100390  (2021) e2100390. (C01)

Mueller C, Trujillo-Miranda M, Maier M, Heath DE, O’Connor AJ, Salehi S, Effects of External Stimulators on Engineered Skeletal Muscle Tissue Maturation, Adv. Mater. Interfaces 8(1) (2021) 2001167. (B03)

Muller SJ, Weigl F, Bezold C, Bacher C, Albrecht K, Gekle S, A hyperelastic model for simulating cells in flow, Biomech Model Mechanobiol 20(2) (2021) 509-520. (B07)

Muir VG, Qazi TH, Shan J, Groll J, Burdick JA, Influence of Microgel Fabrication Technique on Granular Hydrogel Properties, ACS Biomater Sci Eng doi:10.1021/acsbiomaterials.0c01612  (2021). (A02, A06)

Munawar MA, Schubert DW, Highly Oriented Electrospun Conductive Nanofibers of Biodegradable Polymers-Revealing the Electrical Percolation Thresholds, ACS Applied Polymer Materials doi:10.1021/acsapm.0c01332  (2021). (A07)

Munawar MA, Schubert DW, Revealing Electrical and Mechanical Performances of Highly Oriented Electrospun Conductive Nanofibers of Biopolymers with Tunable Diameter, Int J Mol Sci 22(19) (2021). (A07)

Nadernezhad A, Ryma M, Genç H, Cicha I, Jüngst T, Groll J, Melt Electrowriting of Isomalt for High‐Resolution Templating of Embedded Microchannels, Advanced Materials Technologies doi:10.1002/admt.202100221  (2021). (B02)

Neubauer VJ, Dobl A, Scheibel T, Silk-Based Materials for Hard Tissue Engineering, Materials (Basel) 14(3) (2021) 674. (C01)

Neubauer VJ, Trossmann VT, Jacobi S, Dobl A, Scheibel T, Recombinant Spider Silk Gels Derived from Aqueous-Organic Solvents as Depots for Drugs, Angew. Chem., Int. Ed. doi:10.1002/anie.202103147  (2021). (C01)

Pinzner F, Keller T, Mut J, Bechold J, Seibel J, Groll J, Polyoxazolines with a Vicinally Double-Bioactivated Terminus for Biomacromolecular Affinity Assessment, Sensors 21(9) (2021). (A06, B05)

Reakasame S, Dranseikiene D, Schrüfer S, Zheng K, Schubert DW, Boccaccini AR, Development of alginate dialdehyde-gelatin based bioink with methylcellulose for improving printability, Mat Sci Eng C-Mater doi:10.1016/j.msec.2021.112336  (2021) (B03, A07)

Ritter P, Bye LJ, Finol-Urdaneta RK, Lesko C, Adams DJ, Friedrich O, Gilbert DF, A method for high-content functional imaging of intracellular calcium responses in gelatin-immobilized non-adherent cells, Exp Cell Res 395(2) (2020) 112210. (B08)

Ryma M, Tylek T, Bloehbaum J, Fernandez R, Boehm C, Blum C, Kastenmueller W, Gasteiger G, Groll J, Translation of Collagen Ultrastructure to Biomaterial Fabrication for Material Independent but Highly Efficient Topographic Immunomodulation, Adv. Mater. doi:10.1002/adma.202101228  (2021). (B02)

Schmid R, Schmidt SK, Detsch R, Horder H, Blunk T, Schrüfer S, Schubert DW, Fischer L, Thievessen I, Heltmann‐Meyer S, Steiner D, Schneidereit D, Friedrich O, Grüneboom A, Amouei H, Wajant H, Horch RE, Bosserhoff AK, Arkudas A, Kengelbach‐Weigand A, A New Printable Alginate/Hyaluronic Acid/Gelatin Hydrogel Suitable for Biofabrication of In Vitro and In Vivo Metastatic Melanoma Models, Adv. Funct. Mater. doi:10.1002/adfm.202107993 (2021). (C03, A01, A07, B06, B08, C02, C04)

Schneidereit D, Brollochs A, Ritter P, Kreiss L, Mokhtari Z, Beilhack A, Kronke G, Ackermann JA, Faas M, Gruneboom A, Schurmann S, Friedrich O, An advanced optical clearing protocol allows label-free detection of tissue necrosis via multiphoton microscopy in injured whole muscle, Theranostics 11(6) (2021) 2876-2891. (B08)

Schubert DW, Simple Model for the Spreading of Inks in Bioprinting—Revealing Relevant Scaling Laws—Part I Theory, Macromol. Theory Simul. doi:10.1002/mats.202100032  (2021). (A07)

Schubert DW, Allen V, Dippel U, Revealing Novel Power Laws and Quantization in Electrospinning Considering Jet Splitting-Toward Predicting Fiber Diameter and Its Distribution Part II Experimental, Adv. Eng. Mater. 23(3) (2021). (A07)

Shafiee A, Cavalcanti AS, Saidy NT, Schneidereit D, Friedrich O, Ravichandran A, De-Juan-Pardo EM, Hutmacher DW, Convergence of 3D printed biomimetic wound dressings and adult stem cell therapy, Biomaterials 268 (2021) 120558. (B08)

Shan J, Bock T, Keller T, Forster L, Blunk T, Groll J, Tessmar J, TEMPO/TCC as a Chemo Selective Alternative for the Oxidation of Hyaluronic Acid, Molecules 26(19) (2021). (A02)

Sonnleitner D, Schäfer N, Wieland A, Fischer L, Pasberg P, Thievessen I, Lang G, PCL micro-dumbbells – A new class of polymeric particles reveals morphological biofunctionality, Applied Materials Today 24 (2021). (A07, B06)

Sonnleitner D, Sommer C, Scheibel T, Lang G, Approaches to inhibit biofilm formation applying natural and artificial silk-based materials, Mat Sci Eng C-Mater 131 (2021). (A07, C01)

Sonnleitner D, Schrüfer S, Berglund L, Schubert DW, Lang G, Correlating rheology and printing performance of fiber-reinforced bioinks to assess predictive modelling for biofabrication, Journal of Materials Research doi:10.1557/s43578-021-00276-5  (2021). (A07)

Spörrer M, Kah D, Gerum RC, Reischl B, Huraskin D, Dessalles CA, Schneider W, Goldmann WH, Herrmann H, Thievessen I, Clemen CS, Friedrich O, Hashemolhosseini S, Schröder R, Fabry B, doi:10.1101/2021.07.23.453481  (2021). (A01, B08, C02)

Steiner D, Mutschall H, Winkler S, Horch RE, Arkudas A, The Adipose-Derived Stem Cell and Endothelial Cell Coculture System-Role of Growth Factors?, Cells 10(8) (2021). (C04)

Steiner D, Winkler S, Heltmann-Meyer S, Trossmann V, Fey T, Scheibel T, Horch RE, Arkudas A, Enhanced vascularization andde novotissue formation in hydrogels made of engineered RGD-tagged spider silk proteins in the arteriovenous loop model, Biofabrication doi:10.1088/1758-5090/ac0d9b  (2021). (C01, C04)

Uribe-Gomez J, Posada-Murcia A, Shukla A, Ergin M, Constante G, Apsite I, Martin D, Schwarzer M, Caspari A, Synytska A, Salehi S, Ionov L, Shape-Morphing Fibrous Hydrogel/Elastomer Bilayers Fabricated by a Combination of 3D Printing and Melt Electrowriting for Muscle Tissue Regeneration, ACS Appl. Bio Mater. 4(2) (2021) 1720-1730. (B03)

Vielreicher M, Bozec A, Schett G, Friedrich O, Murine Metatarsus Bone and Joint Collagen-I Fiber Morphologies and Networks Studied With SHG Multiphoton Imaging, Front. Bioeng. Biotechnol. 9 (2021) 608383. (B08)

Wieland A, Strissel PL, Schorle H, Bakirci E, Janzen D, Beckmann MW, Eckstein M, Dalton PD, Strick R, Brain and Breast Cancer Cells with PTEN Loss of Function Reveal Enhanced Durotaxis and RHOB Dependent Amoeboid Migration Utilizing 3D Scaffolds and Aligned Microfiber Tracts, Cancers (Basel) 13(20) (2021). (B01)

Winkler S, Mutschall H, Biggemann J, Fey T, Greil P, Korner C, Weisbach V, Meyer-Lindenberg A, Arkudas A, Horch RE, Steiner D, Human Umbilical Vein Endothelial Cell Support Bone Formation of Adipose-Derived Stem Cell-Loaded and 3D-Printed Osteogenic Matrices in the Arteriovenous Loop Model, Tissue Eng Part A 27(5-6) (2021) 413-423. (C04, C03)

Zahoranova A, Luxenhofer R, Poly(2-oxazoline)- and Poly(2-oxazine)-Based Self-Assemblies, Polyplexes, and Drug Nanoformulations-An Update, Adv Healthc Mater 10(6) (2021) 2001382. (A03)

Publications 2020

Aigner TB, Haynl C, Salehi S, O’Connor A, Scheibel T, Nerve guidance conduit design based on self-rolling tubes, Mater Today Bio 5 (2020) 100042. (C01, B03)

Amich J, Mokhtari Z, Strobel M, Vialetto E, Sheta D, Yu Y, Hartweg J, Kalleda N, Jarick KJ, Brede C, Jordan-Garrote AL, Thusek S, Schmiedgen K, Arslan B, Pinnecker J, Thornton CR, Gunzer M, Krappmann S, Einsele H, Heinze KG, Beilhack A, Three-Dimensional Light Sheet Fluorescence Microscopy of Lungs To Dissect Local Host Immune-Aspergillus fumigatus Interactions, mBio 11(1) (2020) 02752-19. (B08)

Apsite I, Constante G, Dulle M, Vogt L, Caspari A, Boccaccini AR, Synytska A, Salehi S, Ionov L, 4D Biofabrication of fibrous artificial nerve graft for neuron regeneration, Biofabrication 12(3) (2020) 035027. (B03)

Bacher C, Bender M, Gekle S, Flow-accelerated platelet biogenesis is due to an elasto-hydrodynamic instability, Proc. Natl. Acad. Sci. U. S. A. 117(32) (2020) 18969-18976. (B07)

Bachmann J, Ehlert E, Becker M, Otto C, Radeloff K, Blunk T, Bauer-Kreisel P, Ischemia-Like Stress Conditions Stimulate Trophic Activities of Adipose-Derived Stromal/Stem Cells, Cells 9(9) (2020) 1935. (C02)

Bakirci E, Schaefer N, Dahri O, Hrynevich A, Strissel P, Strick R, Dalton PD, Villmann C, Melt Electrowritten In Vitro Radial Device to Study Cell Growth and Migration, Adv Biosyst 4(10) (2020) 2000077. (B01)

Berger C, Bjorlykke Y, Hahn L, Muhlemann M, Kress S, Walles H, Luxenhofer R, Raeder H, Metzger M, Zdzieblo D, Matrix decoded – A pancreatic extracellular matrix with organ specific cues guiding human iPSC differentiation, Biomaterials 244 (2020) 119766. (A03)

Bohme I, Bosserhoff A, Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells, Pigm. Cell Melanoma Res. 33(1) (2020) 41-51. (C03)

Cordes S, Mokhtari Z, Bartosova M, Mertlitz S, Riesner K, Shi Y, Mengwasser J, Kalupa M, McGeary A, Schleifenbaum J, Schrezenmeier J, Bullinger L, Diaz-Ricart M, Palomo M, Carrreras E, Beutel G, Schmitt CP, Beilhack A, Penack O, Endothelial damage and dysfunction in acute graft-versus-host disease, Haematologica doi:10.3324/haematol.2020.253716  (2020). (B08)

Dalton PD, Woodfield TBF, Mironov V, Groll J, Advances in Hybrid Fabrication toward Hierarchical Tissue Constructs, Adv Sci (Weinh) 7(11) (2020) 1902953. (A04, B02)

Distler T, Solisito AA, Schneidereit D, Friedrich O, Detsch R, Boccaccini AR, 3D printed oxidized alginate-gelatin bioink provides guidance for C2C12 muscle precursor cell orientation and differentiation via shear stress during bioprinting, Biofabrication 12(4) (2020) 045005. (A01, B06, B08)

Dranseikiene D, Schrufer S, Schubert DW, Reakasame S, Boccaccini AR, Cell-laden alginate dialdehyde-gelatin hydrogels formed in 3D printed sacrificial gel, J. Mater. Sci.: Mater. Med. 31(3) (2020) 31. (A01, A07)

Frischholz S, Berberich O, Bock T, Meffert RH, Blunk T, Resveratrol counteracts IL-1beta-mediated impairment of extracellular matrix deposition in 3D articular chondrocyte constructs, J. Tissue Eng. Regener. Med. 14(7) (2020) 897-908. (A02)

Gensler M, Leikeim A, Mollmann M, Komma M, Heid S, Muller C, Boccaccini AR, Salehi S, Groeber-Becker F, Hansmann J, 3D printing of bioreactors in tissue engineering: A generalised approach, PLoS One 15(11) (2020) 0242615. (B03)

Grosshaus C, Bakirci E, Berthel M, Hrynevich A, Kade JC, Hochleitner G, Groll J, Dalton PD, Melt Electrospinning of Nanofibers from Medical-Grade Poly(epsilon-Caprolactone) with a Modified Nozzle, Small 16(44) (2020) 2003471. (A04)

Hahn L, Maier M, Stahlhut P, Beudert M, Flegler V, Forster S, Altmann A, Toppke F, Fischer K, Seiffert S, Bottcher B, Luhmann T, Luxenhofer R, Inverse Thermogelation of Aqueous Triblock Copolymer Solutions into Macroporous Shear-Thinning 3D Printable Inks, ACS Appl Mater Interfaces 12(11) (2020) 12445-12456. (A03)

Hauptstein J, Bock T, Bartolf-Kopp M, Forster L, Stahlhut P, Nadernezhad A, Blahetek G, Zernecke-Madsen A, Detsch R, Jungst T, Groll J, Tessmar J, Blunk T, Hyaluronic Acid-Based Bioink Composition Enabling 3D Bioprinting and Improving Quality of Deposited Cartilaginous Extracellular Matrix, Adv Healthc Mater 9(15) (2020) 2000737. (A02, A06, B02, B06, Z01)

Hazur J, Detsch R, Karakaya E, Kaschta J, Tessmar J, Schneidereit D, Friedrich O, Schubert DW, Boccaccini AR, Improving alginate printability for biofabrication: establishment of a universal and homogeneous pre-crosslinking technique, Biofabrication 12(4) (2020) 045004. (A01, A02, A07, B06, B08)

Heid S, Boccaccini AR, Advancing bioinks for 3D bioprinting using reactive fillers: A review, Acta Biomater 113 (2020) 1-22. (B03)

Herold HM, Dobl A, Wohlrab S, Humenik M, Scheibel T, Designed Spider Silk-Based Drug Carrier for Redox- or pH-Triggered Drug Release, Biomacromolecules 21(12) (2020) 4904-4912. (C01)

Herrmann M, Engelke K, Ebert R, Muller-Deubert S, Rudert M, Ziouti F, Jundt F, Felsenberg D, Jakob F, Interactions between Muscle and Bone-Where Physics Meets Biology, Biomolecules 10(3) (2020) 432. (B05)

Hoefner C, Muhr C, Horder H, Wiesner M, Wittmann K, Lukaszyk D, Radeloff K, Winnefeld M, Becker M, Blunk T, Bauer-Kreisel P, Human Adipose-Derived Mesenchymal Stromal/Stem Cell Spheroids Possess High Adipogenic Capacity and Acquire an Adipose Tissue-like Extracellular Matrix Pattern, Tissue Eng Part A 26(15-16) (2020) 915-926. (C02)

Janzen D, Bakirci E, Wieland A, Martin C, Dalton PD, Villmann C, Cortical Neurons form a Functional Neuronal Network in a 3D Printed Reinforced Matrix, Adv Healthc Mater 9(9) (2020) 1901630. (B01)

Karakaya E, Fischer L, Hazur J, Boccaccini AR, Thievessen I, Detsch R, Strategies to evaluate alginate based bioinks applying extrusion printingfor biofabrication, Additive Manufacturing Meets Medicine, 2020. (B06, A01)

Kramer JPM, Aigner TB, Petzold J, Roshanbinfar K, Scheibel T, Engel FB, Recombinant spider silk protein eADF4(C16)-RGD coatings are suitable for cardiac tissue engineering, Sci. Rep. 10(1) (2020) 8789. (C01)

Kumari S, Lang G, DeSimone E, Spengler C, Trossmann VT, Lucker S, Hudel M, Jacobs K, Kramer N, Scheibel T, Engineered spider silk-based 2D and 3D materials prevent microbial infestation, Mater. Today 41 (2020) 21-33. (C01, A07)

Kumari S, Lang G, DeSimone E, Spengler C, Trossmann VT, Lucker S, Hudel M, Jacobs K, Kramer N, Scheibel T, Data for microbe resistant engineered recombinant spider silk protein based 2D and 3D materials, Data Brief 32 (2020) 106305. (C01, A07)

Landry MR, DuRoss AN, Neufeld MJ, Hahn L, Sahay G, Luxenhofer R, Sun C, Low dose novel PARP-PI3K inhibition via nanoformulation improves colorectal cancer immunoradiotherapy, Mater Today Bio 8 (2020) 100082. (A03)

Lehmann M, Muller SJ, Gekle S, Efficient viscosity contrast calculation for blood flow simulations using the lattice Boltzmann method, Int. J. Numer. Methods Fluids 92(11) (2020) 1463-1477. (B07)

Levato R, Jungst T, Scheuring RG, Blunk T, Groll J, Malda J, From Shape to Function: The Next Step in Bioprinting, Adv. Mater. 32(12) (2020) 1906423. (A02, B04, Z01)

Liebscher J, Tessmar J, Groll J, In Situ Polymer Analogue Generation of Azlactone Functions at Poly(oxazoline)s for Peptide Conjugation, Macromol. Chem. Phys. 221(1) (2020) 1900500. (A06, B04)

Lorson T, Ruopp M, Nadernezhad A, Eiber J, Vogel U, Jungst T, Luhmann T, Sterilization Methods and Their Influence on Physicochemical Properties and Bioprinting of Alginate as a Bioink Component, ACS Omega 5(12) (2020) 6481-6486. (A03)

Mancini IAD, Schmidt S, Brommer H, Pouran B, Schafer S, Tessmar J, Mensinga A, van Rijen MHP, Groll J, Blunk T, Levato R, Malda J, van Weeren PR, A composite hydrogel-3D printed thermoplast osteochondral anchor as example for a zonal approach to cartilage repair: in vivo performance in a long-term equine model, Biofabrication 12(3) (2020) 035028. (A02)

Mark C, Grundy TJ, Strissel PL, Bohringer D, Grummel N, Gerum R, Steinwachs J, Hack CC, Beckmann MW, Eckstein M, Strick R, O’Neill GM, Fabry B, Collective forces of tumor spheroids in three-dimensional biopolymer networks, eLife 9 (2020) 51912. (C02, B01)

Mechau J, Frank A, Bakirci E, Gumbel S, Jungst T, Giesa R, Groll J, Dalton PD, Schmidt HW, Hydrophilic (AB)n Segmented Copolymers for Melt Extrusion‐Based Additive Manufacturing, Macromol. Chem. Phys. 222(1) (2020). (A04)

Mertgen AS, Trossmann VT, Guex AG, Maniura-Weber K, Scheibel T, Rottmar M, Multifunctional Biomaterials: Combining Material Modification Strategies for Engineering of Cell-Contacting Surfaces, ACS Appl Mater Interfaces 12(19) (2020) 21342-21367. (C01)

Mirzaei Z, Kuth S, Schubert DW, Detsch R, Roether JA, Blunk T, Kordestani SS, Boccaccini AR, Preparation and Characterization of Electrospun Blend Fibrous Polyethylene Oxide:Polycaprolactone Scaffolds to Promote Cartilage Regeneration, Adv. Eng. Mater. 22(9) (2020). (A01, A02, A07, B06)

Muller SJ, Mirzahossein E, Iftekhar EN, Bacher C, Schrufer S, Schubert DW, Fabry B, Gekle S, Flow and hydrodynamic shear stress inside a printing needle during biofabrication, PLoS One 15(7) (2020) 0236371. (B07, A01, A07)

Muller-Deubert S, Ege C, Krug M, Meissner-Weigl J, Rudert M, Bischof O, Jakob F, Ebert R, Phosphodiesterase 10A Is a Mediator of Osteogenic Differentiation and Mechanotransduction in Bone Marrow-Derived Mesenchymal Stromal Cells, Stem Cells Int. 2020 (2020) 7865484. (B05)

Mutschall H, Winkler S, Weisbach V, Arkudas A, Horch RE, Steiner D, Bone tissue engineering using adipose-derived stem cells and endothelial cells: Effects of the cell ratio, J. Cell. Mol. Med. 24(12) (2020) 7034-7043. (C04, C03)

Nadernezhad A, Forster L, Netti F, Adler-Abramovich L, Tessmar J, Groll J, Rheological analysis of the interplay between the molecular weight and concentration of hyaluronic acid in formulations of supramolecular HA/FmocFF hybrid hydrogels, Polym. J. 52(8) (2020) 1007-1012. (A02, B04)

No YJ, Tarafder S, Reischl B, Ramaswamy Y, Dunstan C, Friedrich O, Lee CH, Zreiqat H, High-Strength Fiber-Reinforced Composite Hydrogel Scaffolds as Biosynthetic Tendon Graft Material, ACS Biomater Sci Eng 6(4) (2020) 1887-1898. (B08)

Rausch M, Bohringer D, Steinmann M, Schubert DW, Schrufer S, Mark C, Fabry B, Measurement of Skeletal Muscle Fiber Contractility with High-Speed Traction Microscopy, Biophys. J. 118(3) (2020) 657-666. (A01, A07)

Roshanbinfar K, Esser TU, Engel FB, Stem Cells and Their Cardiac Derivatives for Cardiac Tissue Engineering and Regenerative Medicine, Antioxid. Redox Signaling doi:10.1089/ars.2020.8193  (2020). (C01)

Russell CS, Mostafavi A, Quint JP, Panayi AC, Baldino K, Williams TJ, Daubendiek JG, Hugo Sánchez V, Bonick Z, Trujillo-Miranda M, Shin SR, Pourquie O, Salehi S, Sinha I, Tamayol A, In Situ Printing of Adhesive Hydrogel Scaffolds for the Treatment of Skeletal Muscle Injuries, ACS Appl. Bio Mater. 3(3) (2020) 1568-1579. (B03)

Salehi S, Koeck K, Scheibel T, Spider Silk for Tissue Engineering Applications, Molecules 25(3) (2020) 737. (B03, C01)

Schmid R, Schmidt SK, Hazur J, Detsch R, Maurer E, Boccaccini AR, Hauptstein J, Tessmar J, Blunk T, Schrufer S, Schubert DW, Horch RE, Bosserhoff AK, Arkudas A, Kengelbach-Weigand A, Comparison of Hydrogels for the Development of Well-Defined 3D Cancer Models of Breast Cancer and Melanoma, Cancers 12(8) (2020) 2320. (C03, A01, A02, A07, C02)

Schmidt S, Abinzano F, Mensinga A, Tessmar J, Groll J, Malda J, Levato R, Blunk T, Differential Production of Cartilage ECM in 3D Agarose Constructs by Equine Articular Cartilage Progenitor Cells and Mesenchymal Stromal Cells, Int. J. Mol. Sci. 21(19) (2020) 7071. (A02)

Schrufer S, Sonnleitner D, Lang G, Schubert DW, A Novel Simple Approach to Material Parameters from Commonly Accessible Rheometer Data, Polymers 12(6) (2020) 1276. (A07)

Schubert DW, Novel Theoretical Self‐Consistent Mean‐Field Approach to Describe the Conductivity of Carbon Fiber‐Filled Thermoplastics: Part III—Application of the Concept to Mechanical Properties of Composites and Polymer Solutions, Adv. Eng. Mater. 22(9) (2020). (A07)

Sun W, Starly B, Daly AC, Burdick JA, Groll J, Skeldon G, Shu W, Sakai Y, Shinohara M, Nishikawa M, Jang J, Cho DW, Nie M, Takeuchi S, Ostrovidov S, Khademhosseini A, Kamm RD, Mironov V, Moroni L, Ozbolat IT, The bioprinting roadmap, Biofabrication 12(2) (2020) 022002. (B02, B04)

Tolksdorf J, Horch RE, Gruner JS, Schmid R, Kengelbach-Weigand A, Schubert DW, Werner S, Schneidereit D, Friedrich O, Ludolph I, Size matters-in vitro behaviour of human fibroblasts on textured silicone surfaces with different pore sizes, J. Mater. Sci.: Mater. Med. 31(2) (2020) 23. (C04, B08, A07, C03)

Weizel A, Distler T, Schneidereit D, Friedrich O, Brauer L, Paulsen F, Detsch R, Boccaccini AR, Budday S, Seitz H, Complex mechanical behavior of human articular cartilage and hydrogels for cartilage repair, Acta Biomater 118 (2020) 113-128. (B08)

Publications 2019

Apsite I, Uribe JM, Posada AF, Rosenfeldt S, Salehi S, Ionov L, 4D biofabrication of skeletal muscle microtissues, Biofabrication 12(1) (2019) 015016. (B03)

Bacher C, Gekle S, Computational modeling of active deformable membranes embedded in three-dimensional flows, Phys. Rev. E 99(6-1) (2019) 062418. (B07)

Berberich O, Blöhbaum J, Hölscher-Doht S, Meffert RH, Teßmar J, Blunk T, Groll J, Catechol-modified poly(oxazoline)s with tunable degradability facilitate cell invasion and lateral cartilage integration, J. Ind. Eng. Chem. 80 (2019) 757-769. (A06, B04)

Blohbaum J, Paulus I, Poppler AC, Tessmar J, Groll J, Influence of charged groups on the cross-linking efficiency and release of guest molecules from thiol-ene cross-linked poly(2-oxazoline) hydrogels, J Mater Chem B 7(10) (2019) 1782-1794. (A06)

Condor M, Mark C, Gerum RC, Grummel NC, Bauer A, Garcia-Aznar JM, Fabry B, Breast Cancer Cells Adapt Contractile Forces to Overcome Steric Hindrance, Biophys. J. 116(7) (2019) 1305-1312. (C02)

Daddi-Moussa-Ider A, Kurzthaler C, Hoell C, Zottl A, Mirzakhanloo M, Alam MR, Menzel AM, Lowen H, Gekle S, Frequency-dependent higher-order Stokes singularities near a planar elastic boundary: Implications for the hydrodynamics of an active microswimmer near an elastic interface, Phys. Rev. E 100(3-1) (2019) 032610. (B07)

Distler T, Ruther F, Boccaccini AR, Detsch R, Development of 3D Biofabricated Cell Laden Hydrogel Vessels and a Low-Cost Desktop Printed Perfusion Chamber for In Vitro Vessel Maturation, Macromol. Biosci. 19(9) (2019) 1900245. (B06, A01, B03)

Ertl J, Ortiz-Soto ME, Le TA, Bechold J, Shan J, Tessmar J, Engels B, Seibel J, Tuning the Product Spectrum of a Glycoside Hydrolase Enzyme by a Combination of Site-Directed Mutagenesis and Tyrosine-Specific Chemical Modification, Chem. – Eur. J. 25(26) (2019) 6533-6541. (B05)

Esser TU, Roshanbinfar K, Engel FB, Promoting vascularization for tissue engineering constructs: current strategies focusing on HIF-regulating scaffolds, Expert Opin. Biol. Ther. 19(2) (2019) 105-118. (C01)

Gutmann M, Bechold J, Seibel J, Meinel L, Luhmann T, Metabolic Glycoengineering of Cell-Derived Matrices and Cell Surfaces: A Combination of Key Principles and Step-by-Step Procedures, ACS Biomater Sci Eng 5(1) (2019) 215-233. (A03, B05)

Humenik M, Pawar K, Scheibel T, Nanostructured, Self-Assembled Spider Silk Materials for Biomedical Applications, Adv. Exp. Med. Biol. 1174 (2019) 187-221. (C01)

Kahl M, Gertig M, Hoyer P, Friedrich O, Gilbert DF, Ultra-Low-Cost 3D Bioprinting: Modification and Application of an Off-the-Shelf Desktop 3D-Printer for Biofabrication, Front. Bioeng. Biotechnol. 7 (2019) 184. (B08)

Kengelbach-Weigand A, Tasbihi K, Strissel PL, Schmid R, Marques JM, Beier JP, Beckmann MW, Strick R, Horch RE, Boos AM, Plasticity of patient-matched normal mammary epithelial cells is dependent on autologous adipose-derived stem cells, Sci. Rep. 9(1) (2019) 10722. (C03)

Lübtow MM, Lorson T, Finger T, Gröber‐Becker FK, Luxenhofer R, Combining Ultra‐High Drug‐Loaded Micelles and Injectable Hydrogel Drug Depots for Prolonged Drug Release, Macromol. Chem. Phys. 221(1) (2019). (A03)

Lubtow MM, Mrlik M, Hahn L, Altmann A, Beudert M, Luhmann T, Luxenhofer R, Temperature-Dependent Rheological and Viscoelastic Investigation of a Poly(2-methyl-2-oxazoline)-b-poly(2-iso-butyl-2-oxazoline)-b-poly(2-methyl-2-oxaz oline)-Based Thermogelling Hydrogel, J. Funct. Biomater. 10(3) (2019) 36. (A03)

Hahn L, Maier M, Stahlhut P, Beudert M, Altmann A,  Töppke F, Lühmann T, Luxenhofer R, Inverse Thermogelation of Aqueous Triblock Copolymer Solutions into Macroporous Shear-Thinning 3D Printable Inks, ChemRxiv Published elsewere (2019). (A03)

Madonna R, Van Laake LW, Botker HE, Davidson SM, De Caterina R, Engel FB, Eschenhagen T, Fernandez-Aviles F, Hausenloy DJ, Hulot JS, Lecour S, Leor J, Menasche P, Pesce M, Perrino C, Prunier F, Van Linthout S, Ytrehus K, Zimmermann WH, Ferdinandy P, Sluijter JPG, ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure, Cardiovasc. Res. 115(3) (2019) 488-500. (C01)

McMaster R, Hoefner C, Hrynevich A, Blum C, Wiesner M, Wittmann K, Dargaville TR, Bauer-Kreisel P, Groll J, Dalton PD, Blunk T, Tailored Melt Electrowritten Scaffolds for the Generation of Sheet-Like Tissue Constructs from Multicellular Spheroids, Adv Healthc Mater 8(7) (2019) 1801326. (C02, A04)

Neubauer JW, Hauck N, Mannel MJ, Seuss M, Fery A, Thiele J, Mechanoresponsive Hydrogel Particles as a Platform for Three-Dimensional Force Sensing, ACS Appl Mater Interfaces 11(29) (2019) 26307-26313. (B07)

Ortiz-Soto ME, Reising S, Schlosser A, Seibel J, Structural and functional role of disulphide bonds and substrate binding residues of the human beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1), Sci. Rep. 9(1) (2019) 17993. (B05)

Ostrovidov S, Salehi S, Costantini M, Suthiwanich K, Ebrahimi M, Sadeghian RB, Fujie T, Shi X, Cannata S, Gargioli C, Tamayol A, Dokmeci MR, Orive G, Swieszkowski W, Khademhosseini A, 3D Bioprinting in Skeletal Muscle Tissue Engineering, Small 15(24) (2019) 1805530. (B03)

Roshanbinfar K, Mohammadi Z, Sheikh-Mahdi Mesgar A, Dehghan MM, Oommen OP, Hilborn J, Engel FB, Carbon nanotube doped pericardial matrix derived electroconductive biohybrid hydrogel for cardiac tissue engineering, Biomater. Sci. 7(9) (2019) 3906-3917. (C01)

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Bioreaktor zur 3D-Geweberegeneration von Skelettmuskulatur (‚Tissue Regenerator‘)
Inventors: Oliver Friedrich (B08, Z02) Paul Ritter, Michael Haug
Application number DE 10 2021 211 875, applicant FAU.

Verfahren und Messanordnung zum Ermitteln einer Fließeigenschaft eines Fluids “BERIT” (Best Elongation Rheology Investigative Testing)
Inventors: Dirk W. Schubert (A07), Paul Dalton (A04, B01), Stefan Schrüfer (A07)
DE application number: DE 10 2020 216 545.9., applicant FAU

„Kombiniertes 3D-Druck-Faserspinnen“
Inventor: Leonid Ionov (A08), applicant: UBT

„Gel bildende Block-Polymere“
Inventors: Lukas Hahn, Robert Luxenhofer from A03
Application number EP 3 789 424 A1, applicant JMU.

“Inverse Thermogelling Polyoxazoline Copolymers”
Inventors: Lukas Hahn, Robert Luxenhofer from A03
Application number EP 21 16 4966.0, applicant JMU

Appication: LIGHT SHEET IMAGING DEVICE, SCANNER FOR A LIGHT SHEET IMAGING DEVICE AND METHOD OF OPERATING A LIGHT SHEET IMAGING DEVICE
Inventors: Friedrich O, Dominik Schneidereit D, Sebastian Schürmann S (B08, Z02)
Application number EP 4 109 142 A1

Advanced Strut Investigation Device “ASTRID”
Inventors: D. W. Schubert, Z. Lamberger, G. Lang, S. Schrüfer, J.Groll
DE application number: DE102023206928.8, applicant: JMU, FAU

Extrusionsvorrichtung, Verfahren zur Herstellung einer Hohlstruktur und Verwendung einer Extrusionsvorrichtung
Inventors: Christian Lesko, Oliver Friedrich, Daniel F Gilbert (Z02)
DPMA Patents Nr. 10 2022 203 033