Z02 | Quantitative imaging and analysis of biofabricate quality and maturation

The new project Z02 will develop and provide standardized methods for acquiring, processing, and evaluating imaging data for the entire TRR/SFB, starting off with selected model systems in project areas B and C. In particular, solutions for sample chambers and (fluorescence) imaging, e.g. customized light-sheet microscopy, as well as image data processing and analysis, tuned for the special demands of biofabricates, will be key. Cross-validation of complementary imaging modalities in the three involved laboratories will allow for establishing robust and versatile approaches for the entire collaborative research center.

Prof. Dr. Matthias Weiss
Prof. Dr. Katrin Heinze
Prof. Dr. Dr. Oliver Friedrich 

Julian Bauer

Previous academic education: Master-Thesis
Academic Advisor within SFB TRR225: Prof. Dr. Dr. Oliver Friedrich
Location: FAU-Erlangen, Institute of Medical Biotechnology
Topic: Label-free optical maturation assessment of biofabricated tissue constructs in bioreactor environments tailored for biofabrication.
Main techniques and methodologies to be used: MPM, CAD-design, 3D-printing (FDM, SLS), cell culture, bioreactor process engineering, software development (Python)

Contact: julian.bauer@fau.de

Ivana Jeremic

Previous academic education: Master’s and bachelor’s degree in Physical Chemistry
Academic Advisor within SFB TRR225: Prof. Dr. Matthias Weiss
Location: University of Bayreuth
Topic: Quantitative exploration of the spatiotemporal self-organization of cells in confined geometries via customized lightsheet microscopy.
Main techniques and methodologies to be used: Lightsheet microscopy

Contact:

Joachim Schenk

Previous academic education: Diplom Ingenieur (FH)

Academic Advisor within SFB TRR225: Prof. Dr. Katrin Heinze
Location: Julius-MaximiliansUniversität Würzburg, Rudolf Virchow CenterCenter for Integrative and Translational Bioimaging
Topic: Support of home-built Light Sheet Fluorescence Microscopy (LSFM).
Main techniques and methodologies to be used: Sample admission and sample optimization, Taking care of our home-built microscopes and the needed adaptions to the needs of our collaborators, Planning and constructing a new LSFM, Imaging / data collection of the samples of our collaborators with the existing microscopes, Pre-processing of the data and its quality assurance, Sample and data management of the large files

Contact: joachim.schenk@uni-wuerzburg.de

Dominik Schneidereit

Previous academic education: Master of Science
Academic Advisor within SFB TRR225: Prof. Dr. Dr. Oliver Friedrich
Location: FAU-Erlangen, Institute of Medical Biotechnology
Topic: Neuartige optomechatronische Kombinationstechnologien im Cardio-muskulären Umfeld für Medizin und Lebenswissenschaften
Main techniques and methodologies to be used: Multi photon light sheet microscopy, Optics simulation, 3D CAD and CAM, FFF printing

Contact: dominik.schneidereit@fau.de