A04 | Expansion of the biofabrication window using 2.5D scaffolds made from (AB)n-segmented copolymers
The aim of the project is the expansion of the biofabrication window of bioinks. By using 2.5D scaffolds – a structurally stable substrate – for the bioprinting process a better precision and reproducibility of the bioink depostion can be achieved. For this purpose, new (AB)n-segmented copolymers with hydrophilic soft segments and supramolecular hard segments are developed, which can be processed by Melt Electrospinning Writing. By selective swelling with biological media hydrogel scaffolds are formed covering a wide range of Young’s Moduli and enabling different cellular interactions. Until today, this cannot be realized with conventional biofabrication processes.
Mechau J, Frank A, Böhm C, Giesa R, Dalton PD, Schmidt HW (2018) Melt Electrowriting of water-swelling (AB)n segmented block copolymers, Annual Conference of the International Society for Biofabrication (ISBF), 28 – 31 October, 2018 (Würzburg, Germany).